Nathalie Momplaisir, Pharmacology
Phyllis M. Wise Endowed Graduate Student Award Fund
Nathalie’s work merges multiple disciplines to address complex multifactorial disease states, and her primary interest lies with G protein-coupled receptors (GPCRs), which are common pharmacological targets found throughout the body. Although there is a large amount of literature on the regulatory role of GPCRs, current GPCR drugs target only about 10 percent of all GPCRs that are considered as druggable’ targets. Therefore, discovering new GPCR signaling mechanisms remains popular for drug discovery purposes. Currently, Nathalie is working in the Smrcka lab where she is working on the identification and characterization of the Gi family of these GPCRs. This investigation stems from studies that were done in the lab which reveal the implications of Gai in the regulation of cellular migration, an important process in inflammation, cancer, wound healing, and beyond.
“While still going through this journey, I am grateful to be at the University of Michigan where there are many resources and people that contribute to my continued scientific and professional growth. I am even more grateful for the Phyllis M. Wise Award for providing financial support to me in moments where personal aspects of my life can be stressful and get in the way of my educational path. My educational goals would not be possible without various sponsors like you. Your support brought me one step closer to my vision of being a contributor to the next generation of scientists.”